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Proper treatment of the hyperthyroidism can cause the resolution of the gynecomastia. Medications are known to cause gynecomastia through a number of various mechanisms. These systems include increasing estrogen levels, simulating estrogen, reducing levels of testosterone or other androgens, blocking androgen receptors, increasing prolactin levels, or through unidentified means. High levels of prolactin in the blood (which may happen as a result of specific growths or as a negative effects of particular medications) has actually been associated with gynecomastia.

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Receptors for prolactin and other hormonal agents consisting of insulin-like growth factor 1, insulin-like development aspect 2, luteinizing hormone, progesterone, and human chorionic gonadotropin have actually been found in male breast tissue, however the impact of these various hormones on gynecomastia development is not well comprehended. Medical diagnosis [edit] To identify gynecomastia, a comprehensive history and physical exam are obtained by a doctor.

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Gynecomastia usually provides with bilateral participation of the breast tissue however might occur unilaterally also. A review of the medications or illegal substances an individual takes may expose the reason for gynecomastia. Suggested lab investigations to discover the underlying cause of gynecomastia consist of tests for aspartate transaminase and alanine transaminase to rule out liver disease, serum creatinine to identify if kidney damage exists, and thyroid-stimulating hormone levels to assess for hyperthyroidism.
High levels of prolactin are unusual in people with gynecomastia. If - تثدي الرجل , CG levels are abnormally high, then ultrasound of the testicles should be carried out to look for indications of a hormone-secreting testicular tumor. Markers of testicular, adrenal, or other tumors such as urinary 17-ketosteroid or serum dehydroepiandrosterone might likewise be checked if there is evidence of hormonal imbalance on health examination.
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Differential diagnosis [edit] Other causes of male breast enhancement such as mastitis, breast cancer, pseudogynecomastia, lipoma, sebaceous cyst, dermoid cyst, hematoma, metastasis, ductal ectasia, fat necrosis, or a hamartoma are generally excluded before making the medical diagnosis. Another condition that may be puzzled with gynecomastia is enlargement of the pectoralis muscles. [] Imaging [modify] Mammography is the technique of option for radiologic evaluation of male breast tissue in the medical diagnosis of gynecomastia when breast cancer is presumed on physical examination.